Sweeteners for factor H

Artificial Sweeteners

cloning, expression and purification of the factor h binding protein and its interaction with factor h

background and objective: neisseria meningitidis is a leading cause of meningitis and sepsis worldwide. the factor h binding protein (fhbp) is a key virulence factor of neisseria meningitidis that is able to selectively bind to human factor h, the key regulator of the alternative complement pathway, which it has important implications for meningococcal pathogene- sis and vaccine design. the aim...

Noncariogenic sweeteners. Sugar substitutes for caries control.

The evidence is clear that the incidence of dental caries is related to the frequency of eating sugar. The use of sugar substitutes is a suggested way of reducing sugar intake. A variety of noncariogenic sweeteners exists, but most have no practical value for caries control because of their technical or safety problems, taste, or cost. Urinary bladder tumorigenic effects have been reported in e...

Sugar and Sweeteners

One of the earliest references to sugar in history is a Spanish drawing of a man harvesting honey, dated around 7000 B.C. We know that the Egyptians kept bees for honey, as depicted in tomb drawings as early as 2600 B.C. Research proves something that most of us are already aware of; people are born with a desire for sweet taste. Sugars are widespread in nature and are the building blocks of ca...

Translational mini-review series on complement factor H: structural and functional correlations for factor H.

The 155-kDa glycoprotein, complement factor H (CFH), is a regulator of complement activation that is abundant in human plasma. Three-dimensional structures of over half the 20 complement control protein (CCP) modules in CFH have been solved in the context of single-, double- and triple-module segments. Proven binding sites for C3b occupy the N and C termini of this elongated molecule and may be...